Anabolic steroids: trenbolone, stanozolol, Primobolan

A major specialist in the development and introduction of new drugs, scientist and pharmacologist, who has more than 10 years of scientific research in the field of application of steroids, Seth Roberts in some of his works spoke about the effect of steroids on the human body.

Impact trenbolone

So, derived from nandrolone decanoate – trenbolone has the methyl group being in position 19. He has a great ability to strongly connect not only with progesterone receptors but also androgen. It is likely that such strong ties are a predictor of what trenbolone acts antagonistam in relation to the progesterone receptor. As a rule, it is considered that gynecomastia is caused by antagonists progesterone. Indeed, studies have confirmed that trenbolone is the cause of lowering the body's level of estrogen receptors. In addition, the same strong connection is directly the reason that people, taking this drug can feel a decrease in their libido, and in some cases even to lose it. And this applies to almost all supporters of the drug.

Freely selling on the market, the androgen is not metabolized in skeletal muscle to 3-alpha metabolites. As a result, there is a quick and noticeable gains in size and level of power.

The experiments conducted on zhivotnyh, yielded results suggests that trenbolone is the cause of antiglucocorticoid effects. While there is no evidence that the same effect this drug can have on the human body. Cannot be converted trenbolone and estrogen. Despite the fact that there is a prevailing opinion about the impossibility of reduction, trenbolone is 5-alpha, some scientists in their scientific works show that this steroid manifests much less activity in those tissues in which contains a large number of 5-alpha reductase.

The same effect happens with nandrolone. And, considering that trenbolone is a 19-norsteroid, there is every reason to believe that he is, in fact, is reduced to smaller metabolites. This explains the occurrence of gynecomastia, it is only when the body has stopped produce testosterone, despite the fact that estrogen can not converted from trenbolone. Androgeno-estrogen balance by reducing androgenic stimulation due to the production of such potent 5-alpha reduced androgens. All this is the cause of the high content in the hypothalamus of estrogen signals.

Main problem of the use of trenbolone is that it is almost impossible to get this product manufactureddirectly for human consumption. This drug is called Parabolan, but it is almost completely unavailable for consumption. Besides, now the black market in all trades trenbolona, which is intended for consumption by cattle. This drug is called Finalexam and in clandestine laboratories, this steroid is converted in a suitable injection liquid. This is done by dissolving in a solvent of pellets of implantant, and then the resulting mixture is boiled. As a result, the drug can be injected into the body injection. Also, not a big problem by yourself purchase all the necessary equipment for its production and to effortlessly obtain pellets of trenbolone at home. However, you should always remember about the problem of sterility of such clandestine manufacture. Increases the risk of infections, sepsis, abscess. It is not excluded even the possibility of getting anaphylactic shock, and that's a direct threat of death. In addition, it should be noted that those solvents wood pellets, which are used to produce injection of the mixture, absolutely not intended for those purposes, therefore, the risk of poisoning increases accordingly.

Now trenbolone available for consumption in form of enanthate, acetate or ether hexahydrobenzylcarbonate. Latest take either every day or one-day intervals. Previously this was the product for use in veterinary medicine and it was called Finaject. However, currently this drug is not available. But in clandestine laboratories is the enanthate ester, which can be used at most once a week. But even then, its active supporters, as a rule, prinmat this drug more often. Not very long was the age of the ester hexahydrobenzylcarbonate. Originally sold under the name Parabolan, and designed for human use, it stayed on the market for a very short time. It became a kind of underground signal to manufacturers who are constantly releasing analogues of the ether enanthate. These drugs are even more short century, introduced by injection, once a week or ten days and sometimes once in two weeks. Together with other steroids like trenbolone which is a powerful anabolic that can significantly increase both weight and power. But, except for a pronounced anabolic properties trenbolone has such side effects like acne, hair loss, increased blood pressure, and especially this drug affects the kidneys and the genitourinary system. In fairness it should be admitted that this influence has its confirmation in the scientific literature by conductingrelevant scientific experiments, however, it is known that the kidney is affected by androgen stimulation. Trenbolone, causing hypertension, thus quite strongly harm the kidneys. So taking this steroid should be performed with extreme caution.

The Effect Of Primobolan

Under the name of Primobolan in the market for sale synthetic derivative of dihydrotestosterone is Methenolone. This is one of the types ether acetate, which must be used inside the mouth. However, earlier there are versions of this drug, which was allowed to make the injection. According to many, Primobolan is a totally ineffective drug, so this steroid has received little attention. In addition, deters and its high cost. Another disadvantage for many is the fact that this method of taking the drug is not effective due to dealkilirovania Methenolone 17-alpha. The impression that group 1-matilla able to a certain level to protect it from the effects of the metabolism to 1 - or 2-hydroxymetabolites. But even if this is true, the acetate does not show sufficient oral biological activity, therefore, to achieve good effect, it is necessary to take rather large doses of the drug.

This steroid is not aromatized for the reason that is a derivative of dihydrotestosterone. In addition, it is not too much progestative active. Thus, Primobolan is likely to show inherent properties of the aromatase inhibitor, which is essentially a derivative of dihydrotestosterone. This property has secured a reputation Primobolan steroid "dry gainer", which has quite a small depressing effect. Considering that Methenolone is initially reduced by 5-alpha, this enzyme is not metaboliziruet. However, it is worth remembering that this steroid can metaboliziruetsa directly in skeletal muscle under the influence of 3-alpha dehydrogenase hydroxysteroid. But this metabolism is much less strongly than DHT. As a result of these influences, in his weaker molecule it is possible to observe a weak ratio of androgenic and anabolic activities. Methenolone is also not too much associated with this substance globulin that binds sex hormone. Also, there is no convincing evidence that Methenolone comes in at least minor interaction with the progesterone receptor or glucocorticoid. Thus, Primobolan is not very conducive to gaining weight, but this effect is due to the fact that the fat and water in the body do not stay for long. Difference Primobolan is that ituse when striving to gain quality mass, but to obtain a small number of negative side effects or do not get them at all. But far preferable would be to use this drug by injecting injection. In the case of the use of this drug by women in small amounts, it is even possible to avoid the minor side effects. According to some researchers, intake of Primobolan in limited quantities not even affect the termination of the body to produce natural testosterone. A small impact on the reduction produced by testosterone is due to the fact that it does not go into estrogen. But, nevertheless, this suppression may increase together with increasing amounts of the drug received. Few people know that Methenolone as oxymetholone, increases the body's number of red blood cells. However, Methenolone in any of its form, though the pills, though injections, has never been so common and available drug, like the rest of "reserve". Moreover, what appears on the market, it is worth substantial sums and is not available to all. Methenolone is a product that produces only a limited number of manufacturers and it is a deficit not only in the free market, but on the black market.

Methenolone enanthate is an injectable form of the drug, known on the market under the name of Primobolan Depot. The enanthate ester has the ability to slowly dissolve the tissue, allowing it to enter the body not more often than once in two weeks. But many increase the frequency of its acceptance at two to four times, using a steroid a couple of times a week. If you use Methenolone injection, the effect will be much stronger compared to the oral form of the use of this drug. This is because the injection is not affected by the property of first pass metabolism. And with it a constant need to fight. If you produce evaporation, the air will turn into a substance that is the basis for Methenolone.

Injection enanthate ester together with Methenolone is reasonably strong steroid. The dosage of this drug is 100 ml per week for women and up to 600 ml. for men. To prevent androgenic effects, women should not use the drug more often than every 10 days, and best of all – even less. In General, Methenolone is by far one of the safest steroids on the market. Despite the fact that Methenolone is not alkiliruyutza on the C-17, 1-methyl can cause elevated liver enzymes, even if the drug is administered by injection. However, this effect is much smaller than intime of reception of methandrostenolone and other-17-arylpropionic. Of course, this steroid is not classified as medicines, allows to obtain a lightning effect. This happens due to the fact that it retains water and does not have the power as similar drugs that are introduced into the body by injection such as testosterone or nandrolone. But Methenolone has its fans and adherents, because, despite the absence of quick returns, he has no significant side effects caused by other steroids.

The Effect Of Stanozolol

Stanozolol is a heavily modified version of dihydrotestosterone, and synthetic. Initially this drug was released on the market under the name Winstrol. It in the traditional and familiar structure of steroids with the presence of A-ring was attached an additional ring system. Stanozolol has a rather weak binding abilities, as not well bind to androgen receptor. But the period of its half-life, which lasts nine hours can be considered long enough for this steroid. And it is also one of the factors that led to its low binding capacity. This steroid cannot convert to estrogen metabolite through a process of aromatization, besides, he is already reduced to 5-alpha. Therefore, further regulirovanie not possible. But he has little ability to antiaromatases. Stanozolol is also very bad associated with SGPG globulin that binds sex hormone. Because of this, he is in the vast majority of cases is in a free state. Although directly with glucocorticoid receptors Stanozolol does not interact, it can take in response to the interaction with the protein STBP, which binds the glucocorticoid. In the end, the bound cortisol is rejected and begins to circulate freely. While there is scientifically proven evidence that stanozolol has an impact, and releases from napochechnikov cortisol. As a result, its level lowered, especially if you take this drug on a regular basis. If you stop taking the steroid, you can get the effect of "ricochet", which resulted in the production of cortisol by the body increases dramatically. In addition, the drug can cause severe joint pain.

Despite the fact that stanozolol has been quite a large ratio of androgenic and anabolic activities, he apparently still refers to the androgens. And it antiglucocorticoid properties increase the index of anaboliceski the binding ofandrogenic receptors. Another effect of Stanozolol is its ability to reduce the presence in the body thyroxine binding globulin. But, at the same time, not as much as it happens while taking other steroids anabolic-androgenic group.

Stanozolol can be taken as pills, and injecting. Due to the lack of properties of epirizole, this steroid should be taken every day. Some manufacturers produce injectable stanozolol with a rather large crystals, so often requires a needle of larger diameter for a hassle-free procedure of injection. Also stanozolol is not effective enough, despite a good ratio of anabolic activity relative to androgenic. But this is because he does not possess the property to accumulate water in the body.

ANABOLICS: the Intimate details!

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